In patients with severe renal insufficiency, the dose should be lower and frequent serum magnesium levels must be obtained (see DOSAGE AND ADMINISTRATION). No dosing adjustments are necessary in hepatic insufficiency. If any item is not applicable or no information is available, the space must be marked to indicate that. Magnesium exposed to moist fluorine or chlorine is spontaneously flammable [Mellor 4:267. In the presence of severe renal insufficiency, frequent serum magnesium concentrations must be obtained and the maximum dosage of Magnesium Sulfate is 20 g per 48 hours. The adverse effects of parenterally administered magnesium usually are the result of magnesium intoxication. If you have rectal bleeding or if you do not have a bowel movement after using magnesium sulfate as a laxative, stop using the medication and call your doctor at once. Magnesium Sulphate Page 2 of 4 Ingestion: Never give anything by mouth to an unconscious person. Subsequent intramuscular doses of 4 to 5 g of Magnesium Sulfate may be injected into alternate buttocks every four hours, depending on the continuing presence of the patellar reflex, adequate respiratory function, and absence of signs of magnesium toxicity. It is available in 4% concentration. 1915]. infusion. Rockford, IL 61103 U.S.A. Store at 20° to 25°C (68° to 77°F). Yahoo is part of Verizon Media. Amphotericin B Drink plenty of liquids while you are taking magnesium sulfate. Magnesium exposed to moist fluorine or chlorine is spontaneously flammable [Mellor 4:267. Diuretics Epsom Salts contain mercury. The flexible plastic container is fabricated from polypropylene. Thermal decomposition of Magnesium Sulfate Heptahydrate produces irritating vapors and toxic gases (e.g. These bone abnormalities include skeletal demineralization and osteopenia. Powdered magnesium reacts violently with performic acid [Berichte 48:1139. A mixture of finely divided magnesium and nitric acid is explosive [Pieters 1957. p 28]. Artificial respiration is often required. Because magnesium is removed from the body solely by the kidneys, the drug should be used with caution in patients with renal impairment. Magnesium is excreted solely by the kidney. Digitalis Studies with Magnesium Sulfate in Water for Injection have not been performed to evaluate carcinogenic potential, mutagenic potential or effects on fertility. 77, No. Trade Name: Epsom Salt, Magnesium Sulfate, U.S.P. Medically reviewed by Drugs.com. Because many drugs are excreted in human milk, caution should be exercised when Magnesium Sulfate in Water for Injection is administered to a nursing mother. Dosage Form: injection, solution. It has a role as an anticonvulsant, a cardiovascular drug, a calcium channel blocker, an anaesthetic, a tocolytic agent, an anti-arrhythmia drug, an analgesic and a fertilizer. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Section 15: Other Regulatory Information Federal and State Regulations: Connecticut hazardous material survey. Reflexes may be absent at 10 mEq magnesium/liter, where respiratory paralysis is a potential hazard. Hypocalcemia with signs of tetany secondary to Magnesium Sulfate therapy for eclampsia has been reported. Eye Protection Eye protection is not required during expected product use conditions but may be warranted should a splash potential exist. The central and peripheral effects of magnesium poisoning are antagonized to some extent by intravenous administration of calcium. Solutions in contact with the plastic container may leach out certain chemical components from the plastic in very small amounts; however, biological testing was supportive of the safety of the plastic container materials. Discard unused portion. Monitoring serum magnesium levels and the patient’s clinical status is essential to avoid the consequences of overdosage in toxemia. 3 Product Name: Magnesium Sulfate Injection, USP Respiratory Protection Respiratory protection is not needed during normal product use. In the event of overdosage, artificial ventilation must be provided until a calcium salt can be injected IV to antagonize the effects of magnesium. For the management of pre-eclampsia or eclampsia, intravenous infusions of dilute solutions of magnesium (1% to 8%) are often given in combination with intramuscular injections of 50% Magnesium Sulfate Injection. Continuous administration of Magnesium Sulfate is an unapproved treatment for preterm labor. [See USP Controlled Room Temperature.] Magnesium Sulfate in Water for Injection is a sterile, nonpyrogenic, clear, colorless solution of Magnesium Sulfate heptahydrate in water for injection. Intravenous magnesium should not be given to mothers with toxemia of pregnancy during the two hours preceding delivery. Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in … Fire Extinguishing Media : Use any means suitable for extinguishing surrounding fire. Synonyms : Magnesium / magnesium, borings / magnesium, metal / magnesium, ribbons / magnesium, scalpings / magnesium, sheet / magnesium, turnings BIG no : 10761 1.2. Water can permeate from inside the container into the overwrap but not in amounts sufficient to affect the solution significantly. Fire: Magnesium Sulfate is not flammable. Select one or more newsletters to continue. 1. At this level respiratory paralysis may occur. Is Magnesium Sulfate Flammable. The pH is 4.5 (3.5 to 6.5). Drug induced renal losses of magnesium occur with the following drugs or drug classes: Aminoglycosides (See OVERDOSAGE.). Use appropriate media for adjacent fire. I found this out recently from my son's doctor. In addition, cases of neonatal fracture have been reported. Fireworks use magnesium, both in aerial fireworks and in hand-held sparklers. As serum magnesium rises above 4 mEq/liter, the deep tendon reflexes are first decreased and then disappear as the serum level approaches 10 mEq/liter. Follow all directions on the product package. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. The rate of I.V. For advice, contact the … Fiber cement panels are non-combustible building materials and offer amazing performance in fireproof, bending strength and impact resistance. Pain. Magnesium sulfate taken orally should produce a bowel movement within 30 minutes to 6 hours. Hypermagnesemia in the newborn may require resuscitation and assisted ventilation via endotracheal intubation or intermittent positive pressure ventilation as well as IV calcium. In magnesium: Principal compounds. Cyclosporine Magnesium Sulfate in Water for Injection should be administered slowly to avoid producing hypermagnesemia. Flame temperatures of magnesium and magnesium alloys can reach 3,100 °C (5,610 °F), although flame height above the burning metal is usually less than 300 mm (12 in). Subcutaneous physostigmine, 0.5 to 1 mg may be helpful. When administered by continuous IV infusion (especially for more than 24 hours preceding delivery) to control convulsions in a toxemic woman, the newborn may show signs of magnesium toxicity, including neuromuscular or respiratory depression. dose, some clinicians administer 1 to 2 g/hour by constant I.V. Cisplatin. You can change your choices at any time by visiting Your Privacy Controls. How to use Magnesium Sulfate. Specific hazards arising from Magnesium Sulfate in Water for Injection is a sterile, nonpyrogenic, clear, colorless solution of Magnesium Sulfate heptahydrate in water for injection. Use a mercury free magnesium sulfate cream ( Kirkman's Labs) sells this. Generic Name: Magnesium Sulfate heptahydrate Information about your device and internet connection, including your IP address, Browsing and search activity while using Verizon Media websites and apps. Data sources include IBM Watson Micromedex (updated 7 Dec 2020), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 3 Dec 2020) and others. Available for Android and iOS devices. Sulfate mgo board is also known as MGSO4 board, magnesium sulfate board or chloride free mgo board which is a light weight non-flammable panel product. Started to soak it in Epsom salts. Intravenously administered magnesium is immediately absorbed. The shortest duration of treatment that can lead to fetal harm is not known. Magnesium sulfate is a magnesium salt having sulfate as the counterion. Been working two jobs on it. Approximately 1-2% of total body magnesium is located in the extracellular fluid space. Magnesium sulfate, anhydrous >99 7487-88-9 231-298-2 MgSO 4 120.37 g/mol 4. To initiate therapy, 4 g of Magnesium Sulfate in Water for Injection may be administered intravenously. Magnesium Sulfate, 2.25% w/v Safety Data Sheet according to Federal Register / Vol. The administration of Magnesium Sulfate in Water for Injection outside of its approved indication in pregnant women should be by trained obstetrical personnel in a hospital setting with appropriate obstetrical care facilities. With low doses only flushing and sweating occur, but larger doses cause lowering of blood pressure. Magnesium acts peripherally to produce vasodilation. It is not known whether this drug is excreted in human milk. Magnesium intoxication is manifested by a sharp drop in blood pressure and respiratory paralysis. Magnesium is highly flammable, especially when powdered or shaved into thin strips, though it is difficult to ignite in mass or bulk. Magnesium Sulfate Heptahydrate is an odorless, colorless to white solid in crystalline form. Immediate medical attention and special treatment, if necessary No additional information available … OSHA Vacated PELs: Magnesium sulfate, anhydrous: No OSHA Vacated PELs are listed for this chemical. Special protective equipment and precautions for firefighters Wear self-contained, approved breathing apparatus and full protective clothing, including eye protection and boots. Indicated for the latest medication news, new drug approvals, alerts and updates having Sulfate as the counterion whether! You can change your choices at any time by visiting your Privacy Controls unconscious person pills, check interactions set! Drugs.Com newsletters for the latest medication news, new drug approvals, alerts and updates chemically designated MgSO4 7H2O! 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